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Influence of dispersion medium on nanomaterial-induced pulmonary inflammation and DNA strand breaks: Investigation of carbon black, carbon nanotubes and three titanium dioxide nanoparticles
(Peer reviewed; Journal article, 2017)Intratracheal instillation serves as a model for inhalation exposure. However, for this, materials are dispersed in appropriate media that may influence toxicity. We tested whether different intratracheal instillation ... -
Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes
(Peer reviewed; Journal article, 2018)The effects of long-term chronic exposure of human lung cells to multi-walled carbon nanotubes (MWCNT) and their impact upon cellular proteins and lipids were investigated. Since the lung is the major target organ, an in ... -
Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study
(Peer reviewed; Journal article, 2017)Background Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to ... -
Maternal exposure to a mixture of persistent organic pollutants (POPs) affects testis histology, epididymal sperm count and induces sperm DNA fragmentation in mice
(Peer reviewed; Journal article, 2017)Persistent organic pollutants (POPs) are widespread throughout the environment and some are suspected to induce reproductive toxicity. As animals and humans are exposed to complex mixtures of POPs, it is reasonable to ... -
Essential and non-essential trace elements among working populations in Ghana
(Peer reviewed; Journal article, 2017)Background Lead battery repair workers (LBRW) and electronic repair workers (ERW) may be exposed to inorganic components during work. This study aimed at determining essential and non-essential trace elements in male LBRW, ...