Browsing Brage by Author "Shete, Sanjay S."
Now showing items 1-5 of 5
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Gene–gene interaction of AhRwith and within the Wntcascade afects susceptibility to lung cancer
Rosenberger, Albert; Muttray, Nils; Hung, Rayjean J.; Christiani, David C.; Caporaso, Neil E.; Liu, Geoffrey; Bojesen, Stig E.; Le Marchand, Loic; Albanes, Demetrios; Aldrich, Melinda C.; Tardon, Adonina; Fernández‑Tardón, Guillermo; Rennert, Gad; Field, John K.; Davies, Michael P. A.; Liloglou, Triantafllos; Kiemeney, Lambertus A.; Lazarus, Philip; Wendel, Bernadette; Haugen, Aage; Zienolddiny, Shanbeh; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Duell, Eric J.; Arnold, Susanne M.; Goodman, Gary G.; Chen, Chu; Doherty, Jennifer A.; Taylor, Fiona; Cox, Angela; Voll, Penella J.; Risch, Angela; Muley, Thomas R.; Johansson, Mikael; Brennan, Paul; Landi, Maria Teresa; Shete, Sanjay S.; Amos, Christopher I.; Bickeboller, Heike (Peer reviewed; Journal article, 2022)Background: Aberrant Wnt signalling, regulating cell development and stemness, infuences the development of many cancer types. The Aryl hydrocarbon receptor (AhR) mediates tumorigenesis of environmental pollutants. Complex ... -
Genome-wide association meta-analysis identifies pleiotropic risk loci for aerodigestive squamous cell cancers
Lesseur, Corina; Ferreiro-Iglesias, Aida; McKay, James D.; Bossé, Yohan; Johansson, Mattias; Gaborieau, Valerie; Landi, Maria Teresa; Christiani, David C.; Caporaso, Neil E.; Bojesen, Stig E.; Amos, Christopher I.; Shete, Sanjay S.; Liu, Geoffrey; Rennert, Gadi; Albanes, Demetrius; Aldrich, Melinda C.; Tardon, Adonina; Chen, Chu; Triantafillos, Liloglou; Field, John K.; Teare, Marion Dawn; Kiemeney, Lambertus A.; Diergaarde, Brenda; Ferris, Robert L.; Zienolddiny, Shanbeh; Lam, Stephen; Olshan, Andrew F.; Weissler, Mark C.; Lacko, Martin; Risch, Angela; Bickeböller, Heike; Ness, Andy R.; Thomas, Steve; Le Marchand, Loïc; Schabath, Matthew B.; Wunsch-Filho, Victor; Tajara, Eloiza H.; Andrew, Angeline S.; Clifford, Gary M.; Lazarus, Philip; Grankvist, Kjell; Johansson, Mikael; Arnold, Susanne; Melander, Olle; Brunnström, Hans; Boccia, Stefania; Cadoni, Gabriella; Timens, Wim; Obeidat, Ma’en; Xiao, Xiangjun; Houlston, Richard S.; Hung, Rayjean J.; Brennan, Paul (Peer reviewed; Journal article, 2021)Squamous cell carcinomas (SqCC) of the aerodigestive tract have similar etiological risk factors. Although genetic risk variants for individual cancers have been identified, an agnostic, genome-wide search for shared genetic ... -
Genome-wide interaction analysis identified low-frequency variants with sex disparity in lung cancer risk
Li, Yafang; Xiao, Xiangjun; Li, Jianrong; Byun, Jinyoung; Cheng, Chao; Bossé, Yohan; McKay, James; Albanes, Demetrios; Lam, Stephen; Tardon, Adonina; Chen, Chu; Bojesen, Stig E.; Landi, Maria T.; Mattias, Johansson; Risch, Angela; Bickeböller, Heike; Wichmann, H-Erich; Christiani, David C.; Rennert, Gad; Arnold, Susanne; Goodman, Gary; Field, John K.; Davies, Michael P.A .; Shete, Sanjay S.; Le Marchand, Loic; Melander, Olle; Brunnström, Hans; Liu, Geoffrey; Hung, Rayjean J.; Andrew, Angeline S.; Kiemeney, Lambertus A.; Shen, Hongbing; Sun, Ryan; Zienolddiny, Shanbeh; Grankvist, Kjell; Johansson, Mikael; Caporaso, Neil; Teare, Dawn M.; Hong, Yun-Chul; Lazarus, Philip; Schabath, Matthew B.; Aldrich, Melinda C.; Schwartz, Ann G.; Gorlov, Ivan; Purrington, Kristen; Yang, Ping; Liu, Yanhong; Han, Younghun; Bailey-Wilson, Joan B.; Pinney, Susan M.; Bailey-Wilson, Joan E.; Mandal, Diptasri; Willey, James C.; Gaba, Colette; Brennan, Paul; Amos, Christopher I. (Peer reviewed; Journal article, 2022)Differences by sex in lung cancer incidence and mortality have been reported which cannot be fully explained by sex differences in smoking behavior, implying existence of genetic and molecular basis for sex disparity in ... -
Iam hiQ - a novel pair of accuracy indices for imputed genotypes
Rosenberger, Albert; Tozzi, Viola; Bickeböller, Heike; Hung, Rayjean J.; Christiani, David C.; Caporaso, Neil E.; Liu, Geoffrey; Bojesen, Stig E.; Le Marchand, Loic; Albanes, Demetrios; Aldrich, Melinda C.; Tardon, Adonina; Fernandez-Tardon, Guillermo; Rennert, Gad; Field, John K.; Davies, Michael; Liloglou, Triantafillos; Kiemeney, Lambertus A.; Lazarus, Philip; Haugen, Aage; Zienolddiny, Shanbeh; Lam, Stephen; Schabath, Matthew B.; Andrew, Angeline S.; Duell, Eric J.; Arnold, Susanne M.; Brunnström, Hans; Melander, Olle; Goodman, Gary E.; Chen, Chu; Doherty, Jennifer A.; Teare, M. Dawn; Cox, Angela; Woll, Penella J.; Risch, Angela; Muley, Thomas R.; Johansson, Mikael; Brennan, Paul; Landi, Maria Teresa; Shete, Sanjay S.; Amos, Christopher I. (Peer reviewed; Journal article, 2022)Background: Imputation of untyped markers is a standard tool in genome-wide association studies to close the gap between directly genotyped and other known DNA variants. However, high accuracy with which genotypes are ... -
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
Kachuri, Linda; Johansson, Mattias; Rashkin, Sara R.; Graff, Rebecca E.; Bossé, Yohan; Manem, Venkata; Caporaso, Neil E.; Landi, Maria Teresa; Christiani, David C.; Vineis, Paolo; Liu, Geoffrey; Scelo, Ghislaine; Zaridze, David; Shete, Sanjay S.; Albanes, Demetrius; Aldrich, Melinda C.; Tardón, Adonina; Rennert, Gad; Chen, Chu; Goodman, Gary E.; Doherty, Jennifer A.; Bickeboller, Heike; Field, John K.; Davies, Michael P.; Teare, M. Dawn; Kiemeney, Lambertus A.; Bojesen, Stig E.; Haugen, Aage; Zienolddiny, Shanbeh; Lam, Stephen; Le Marchand, Loïc; Cheng, Iona; Schabath, Matthew B.; Duell, Eric J.; Andrew, Angeline S.; Manjer, Jonas; Lazarus, Philip; Arnold, Susanne; McKay, James D.; Emami, Nima C.; Warkentin, Matthew T.; Brhane, Yonathan; Obeidat, Ma’en; Martin, Richard M.; Relton, Caroline; Smith, George Davey; Haycock, Philip C.; Amos, Christopher I.; Brennan, Paul; Witte, John S.; Hung, Rayjean J. (Peer reviewed; Journal article, 2020)Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and ...