Browsing Brage by Author "Smith, George Davey"

Now showing items 1-3 of 3

    • Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility 

      Kachuri, Linda; Johansson, Mattias; Rashkin, Sara R.; Graff, Rebecca E.; Bossé, Yohan; Manem, Venkata; Caporaso, Neil E.; Landi, Maria Teresa; Christiani, David C.; Vineis, Paolo; Liu, Geoffrey; Scelo, Ghislaine; Zaridze, David; Shete, Sanjay S.; Albanes, Demetrius; Aldrich, Melinda C.; Tardón, Adonina; Rennert, Gad; Chen, Chu; Goodman, Gary E.; Doherty, Jennifer A.; Bickeboller, Heike; Field, John K.; Davies, Michael P.; Teare, M. Dawn; Kiemeney, Lambertus A.; Bojesen, Stig E.; Haugen, Aage; Zienolddiny, Shanbeh; Lam, Stephen; Le Marchand, Loïc; Cheng, Iona; Schabath, Matthew B.; Duell, Eric J.; Andrew, Angeline S.; Manjer, Jonas; Lazarus, Philip; Arnold, Susanne; McKay, James D.; Emami, Nima C.; Warkentin, Matthew T.; Brhane, Yonathan; Obeidat, Ma’en; Martin, Richard M.; Relton, Caroline; Smith, George Davey; Haycock, Philip C.; Amos, Christopher I.; Brennan, Paul; Witte, John S.; Hung, Rayjean J. (Peer reviewed; Journal article, 2020)
      Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and ...

    • Mendelian randomization and mediation analysis of leukocyte telomere length and risk of lung and head and neck cancers 

      Kachuri, Linda; Saarela, Olli; Bojesen, Stig E.; Smith, George Davey; Liu, Geoffrey; Landi, Maria Teresa; Caporaso, Neil E.; Christiani, David C.; Johansson, Mattias; Panico, Salvatore; Overvad, Kim; Trichopoulou, Antonia; Vineis, Paolo; Scelo, Ghislaine; Zaridze, David; Wu, Xifeng; Albanes, Demetrius; Diergaarde, Brenda; Lagiou, Pagona; Macfarlane, Gary J.; Aldrich, Melinda; Tardon, Adonina; Rennert, Gad; Olshan, Andrew F.; Weissler, Mark C.; Chen, Chu; Goodman, Gary E.; Doherty, Jennifer A.; Ness, Andrew R.; Bickeboller, Heike; Wichmann, H. Erich; Risch, Angela; Field, John K.; Teare, M. Dawn; Kiemeney, Lambertus; van der Heijden, Erik H. F. M.; Carroll, June C.; Haugen, Aage; Zienolddiny, Shanbeh; Skaug, Vidar; Wunsch-Filho, Victor; Tajara, Eloiza H.; Moyses, Raquel Ajub; Nunes, Fabio Daumas; Lam, Stephen; Eluf-Neto, Jose; Lacko, Martin; Peters, Wilbert HM; Le Marchand, Loïc; Duell, Eric J.; Andrew, Angeline S.; Franceschi, Silvia; Schabath, Matthew B.; Manjer, Jonas; Arnold, Susanne; Lazarus, Philip; Mukeriya, Anush; Swiatkowska, Beata; Janout, Vladimir; Holcátová, Ivana; Stojsic, Jelena; Mates, Dana; Lissowska, Jolanta; Boccia, Stefania; Lesseur, Corina; Zong, Xuchen; McKay, James D.; Brennan, Paul; Amos, Christopher I.; Hung, Rayjean J. (Peer reviewed; Journal article, 2018)
      Background: Evidence from observational studies of telomere length (TL) has been conflicting regarding its direction of association with cancer risk. We investigated the causal relevance of TL for lung and head and neck ...

    • Obesity, metabolic factors and risk of different histological types of lung cancer: A Mendelian randomization study 

      Carreras-Torres, Robert; Haycock, Philip C.; Wade, Kaitlin H.; Relton, Caroline L.; Martin, Richard M.; Smith, George Davey; Albanes, Demetrius; Aldrich, Melinda C.; Andrew, Angeline S.; Arnold, Susanne M.; Bickeböller, Heike; Bojesen, Stig E.; Brunnström, Hans; Manjer, Jonas; Brüske, Irene; Caporaso, Neil E.; Chen, Chu; Christiani, David C.; Christian, W. Jay; Doherty, Jennifer A.; Duell, Eric J.; Field, John K.; Davies, Michael P. A.; Marcus, Michael W.; Goodman, Gary E.; Grankvist, Kjell; Haugen, Aage; Hong, Yun-Chul; Kiemeney, Lambertus A.; van der Heijden, Erik H. F. M.; Kraft, Peter; Johansson, Mikael B.; Lam, Stephen; Landi, Maria Teresa; Lazarus, Philip; Le Marchand, Loïc; Liu, Geoffrey; Melander, Olle; Park, Sungshim L.; Rennert, Gad; Risch, Angela; Haura, Eric B.; Scelo, Ghislaine; Zaridze, David; Mukeriya, Anush; Savić, Milan; Lissowska, Jolanta; Swiatkowska, Beata; Janout, Vladimir; Holcatova, Ivana; Mates, Dana; Schabath, Matthew B.; Shen, Hongbing; Tardon, Adonina; Teare, M Dawn; Woll, Penella; Tsao, Ming-Sound; Wu, Xifeng; Yuan, Jian-Min; Hung, Rayjean J.; Amos, Christopher I.; McKay, James; Brennan, Paul (Peer reviewed; Journal article, 2017)
      Background Assessing the relationship between lung cancer and metabolic conditions is challenging because of the confounding effect of tobacco. Mendelian randomization (MR), or the use of genetic instrumental variables to ...