Browsing Brage by Author "Tardón, Adonina"
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Comprehensive functional annotation of susceptibility variants identifies genetic heterogeneity between lung adenocarcinoma and squamous cell carcinoma
Qin, Na; Li, Yuancheng; Wang, Cheng; Zhu, Meng; Dai, Juncheng; Hong, Tongtong; Albanes, Demetrius; Lam, Stephen; Tardón, Adonina; Chen, Chu; Goodman, Gary; Bojesen, Stig E.; Landi, Maria Teresa; Johansson, Mattias; Risch, Angela; Wichmann, H-Erich; Bickeboller, Heike; Rennert, Gadi; Arnold, Susanne; Brennan, Paul; Field, John K.; Shete, Sanjay; Le Marchand, Loic; Melander, Olle; Brunnstrom, Hans; Liu, Geoffrey; Hung, Rayjean J.; Andrew, Angeline; Kiemeney, Lambertus A.; Zienolddiny, Shanbeh; Grankvist, Kjell; Johansson, Mikael; Caporaso, Neil; Woll, Penella; Lazarus, Philip; Schabath, Matthew B.; Aldrich, Melinda C.; Stevens, Victoria L.; Jin, Guangfu; Christiani, David C.; Hu, Zhibin; Amos, Christopher I.; Ma, Hongxia; Shen, Hongbing (Peer reviewed; Journal article, 2020)Although genome-wide association studies have identified more than eighty genetic variants associated with non-small cell lung cancer (NSCLC) risk, biological mechanisms of these variants remain largely unknown. By integrating ... -
Immune-mediated genetic pathways resulting in pulmonary function impairment increase lung cancer susceptibility
Kachuri, Linda; Johansson, Mattias; Rashkin, Sara R.; Graff, Rebecca E.; Bossé, Yohan; Manem, Venkata; Caporaso, Neil E.; Landi, Maria Teresa; Christiani, David C.; Vineis, Paolo; Liu, Geoffrey; Scelo, Ghislaine; Zaridze, David; Shete, Sanjay S.; Albanes, Demetrius; Aldrich, Melinda C.; Tardón, Adonina; Rennert, Gad; Chen, Chu; Goodman, Gary E.; Doherty, Jennifer A.; Bickeboller, Heike; Field, John K.; Davies, Michael P.; Teare, M. Dawn; Kiemeney, Lambertus A.; Bojesen, Stig E.; Haugen, Aage; Zienolddiny, Shanbeh; Lam, Stephen; Le Marchand, Loïc; Cheng, Iona; Schabath, Matthew B.; Duell, Eric J.; Andrew, Angeline S.; Manjer, Jonas; Lazarus, Philip; Arnold, Susanne; McKay, James D.; Emami, Nima C.; Warkentin, Matthew T.; Brhane, Yonathan; Obeidat, Ma’en; Martin, Richard M.; Relton, Caroline; Smith, George Davey; Haycock, Philip C.; Amos, Christopher I.; Brennan, Paul; Witte, John S.; Hung, Rayjean J. (Peer reviewed; Journal article, 2020)Impaired lung function is often caused by cigarette smoking, making it challenging to disentangle its role in lung cancer susceptibility. Investigation of the shared genetic basis of these phenotypes in the UK Biobank and ...