Browsing Brage by Author "Teare, Dawn"
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Elevated platelet count appears to be causally associated with increased risk of lung cancer. A Mendelian randomization analysis
Zhu, Ying; Wei, Yongyue; Zhang, Ruyang; Dong, Xuesi; Shen, Sipeng; Zhao, Yang; Bai, Jianling; Albanes, Demetrius; Caporaso, Neil E.; Landi, Maria Teresa; Zhu, Bin; Chanock, Stephen J.; Gu, Fangyi; Lam, Stephen; Ming-Sound, Tsao; Shepherd, Frances A.; Tardon, Adonina; Fernández-Somoano, Ana; Fernandez-Tardon, Guillermo; Chen, Chu; Barnett, Matthew J.; Doherty, Jennifer; Bojesen, Stig E.; Johansson, Mattias; Brennan, Paul; McKay, James D.; Carreras-Torres, Robert; Muley, Thomas; Risch, Angela; Wichmann, Heinz-Erich; Bickeboller, Heike; Rosenberger, Albert; Rennert, Gad; Saliba, Walid; Arnold, Susanne; Field, John K.; Davies, Michael P.A.; Marcus, Michael W.; Wu, Xifeng; Ye, Yuanqing; Le Marchand, Loic; Wilkens, Lynne R.; Melander, Olle; Manjer, Jonas; Brunnström, Hans; Hung, Rayjean J.; Liu, Geoffrey; Brhane, Yonathan; Kachuri, Linda; Andrew, Angeline S.; Duell, Eric J.; Kiemeney, Lambertus A.; van der Heijden, Erik H. F. M.; Haugen, Aage; Zienolddiny, Shanbeh; Skaug, Vidar; Grankvist, Kjell; Johansson, Mikael; Woll, Penella; Cox, Angela; Taylor, Fiona; Teare, Dawn; Lazarus, Philip; Schabath, Matthew B.; Aldrich, Melinda C.; Houlston, Richard S.; McLaughlin, John; Stevens, Victoria L.; Shen, Hongbing; Hu, Zhibin; Dai, Juncheng; Amos, Christopher I.; Han, Younghun; Zhu, Dakai; Goodman, Gary E.; Chen, Feng; Christiani, David C. (Peer reviewed; Journal article, 2019)Background: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung ... -
Systematic analyses of regulatory variants in DNase I hypersensitive sites identified two novel lung cancer susceptibility loci
Dai, Juncheng; Li, Zhihua; Amos, Christopher I.; Hung, Rayjean J.; Tardon, Adonina; Andrew, Angeline; Chen, Chu; Christiani, David C.; Albanes, Demetrios; van der Heijden, Erik H. F. M.; Duell, Eric J.; Rennert, Gadi; McKay, James D.; Yuan, Jian-Min; Field, John K.; Manjer, Jonas; Grankvist, Kjell; Le Marchand, Loïc; Teare, Dawn; Schabath, Matthew B.; Aldrich, Melinda C.; Tsao, Ming-Sound; Lazarus, Philip; Lam, Stephen; Bojesen, Stig E.; Arnold, Susanne; Wu, Xifeng; Haugen, Aage; Janout, Vladimir; Johansson, Mikael; Brhane, Yonathan; Fernandez-Somoano, Ana; Kiemeney, Lambertus A.; Davies, Michael; Zienolddiny, Shanbeh; Hu, Zhibin; Shen, Hongbing (Peer reviewed; Journal article, 2019)DNase I hypersensitive sites (DHS) are abundant in regulatory elements, such as promoter, enhancer and transcription factor binding sites. Many studies have revealed that disease-associated variants were concentrated in ...