Blar i Brage på forfatter "Skaug, Vidar"

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    • A Two-Gene Prognostic Classifier for Early-Stage Lung Squamous Cell Carcinoma in Multiple Large-Scale and Geographically Diverse Cohorts 

      Noro, Rintaro; Ishigame, Teruhide; Walsh, Naomi; Shiraishi, Kouya; Robles, Ana I.; Ryan, Bríd M.; Schetter, Aaron J.; Bowman, Elise D.; Welsh, Judith A.; Seike, Masahiro; Gemma, Akihiko; Skaug, Vidar; Mollerup, Steen Kristen; Haugen, Aage; Yokota, Jun; Kohno, Takashi; Harris, Curtis C. (Peer reviewed; Journal article, 2017)
      Introduction: There are no validated molecular methods that prospectively identify patients with surgically resected lung squamous cell carcinoma (SCC) at high risk for recurrence. By focusing on the expression of genes ...

    • Aktuelle artikler om arbeidsmiljø 

      Skaug, Vidar; Nesland, Jan M. (HD; 998/89, Research report, 1989)

    • An integrated prognostic classifier for Stage I lung adenocarcinoma based on mRNA, microRNA, and DNA methylation biomarkers 

      Robles, Ana I.; Arai, Eri; Mathé, Ewy A.; Okayama, Hirokazu; Schetter, Aaron J.; Brown, Derek; Petersen, David; Bowman, Elise D.; Noro, Rintaro; Welsh, Judith A.; Edelman, Daniel C.; Stevenson, Holly S.; Wang, Yonghong; Tsuchiya, Naoto; Kohno, Takashi; Skaug, Vidar; Mollerup, Steen Kristen; Haugen, Aage; Meltzer, Paul S.; Yokota, Jun; Kanai, Yae; Harris, Curtis C. (Peer reviewed; Journal article, 2015)
      Introduction: Up to 30% stage I lung cancer patients suffer recurrence within 5 years of curative surgery. We sought to improve existing protein-coding gene and microRNA expression prognostic classifiers by incorporating ...

    • Asbest i bygninger : helserisikovurdering, prøvetaking, analyse og kontroll ved asbestsanering 

      Skaug, Vidar; Skogstad, Asbjørn (HD; 991/89, Research report, 1989)

    • Association of the FAM46A gene VNTRs and BAG6 rs3117582 SNP with non small cell lung cancer (NSCLC) in Croatian and Norwegian populations 

      Etokebe, Godfrey; Zienolddiny, Shanbeh; Kupanovac, Zeljko; Enersen, Morten; Balen, Sanja; Flego, Velkjo; Bulat-Kardum, Ljiljana; Radojčić-Badovinac, Anđelka; Skaug, Vidar; Bakke, Per S.; Haugen, Aage; Dembic, Zlatko (Journal article, 2015)

    • Carbon Nanotube Emissions from Arc Discharge Production: Classification of Particle Types with Electron Microscopy and Comparison with Direct Reading Techniques 

      Ludvigsson, Linus; Isaxon, Christina; Nilsson, Patrik T.; Tinnerberg, Hakan; Messing, Maria E.; Rissler, Jenny; Skaug, Vidar; Gudmundsson, Anders; Bohgar, Mats; Hedmer, Maria; Pagels, Joakim (Peer reviewed; Journal article, 2016)
      Introduction: An increased production and use of carbon nanotubes (CNTs) is occurring worldwide. In parallel, a growing concern is emerging on the adverse effects the unintentional inhalation of CNTs can have on humans. ...

    • Cellular Responses of Industrially Relevant Silica Dust on Human Glial Cells In Vitro 

      Arnoldussen, Yke Jildouw; Ervik, Torunn Kringlen; Eriksen, Mina Baarnes; Kero, Ida; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2019)
      Despite the rigorous emission control measures in the ferroalloy industry, there are still emissions of dust during the production of various alloys. Dust particles were collected from laboratory scale processes where oxide ...

    • Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes 

      Phuyal, Santosh; Kasem, Mayes; Knittelfelder, Oskar; Sharma, Animesh; Fonseca, Davi de Miranda; Vebraite, Vaineta; Shaposhnikov, Sergey; Slupphaug, Geir; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2018)
      The effects of long-term chronic exposure of human lung cells to multi-walled carbon nanotubes (MWCNT) and their impact upon cellular proteins and lipids were investigated. Since the lung is the major target organ, an in ...

    • CHRNA5 risk variant predicts delayed smoking cessation and earlier lung cancer diagnosis—A meta-analysis 

      Chen, Li-Shiun; Hung, Rayjean J.; Baker, Timothy B.; Horton, Amy; Culverhouse, Rob; Saccone, Nancy; Cheng, Iona; Deng, Bo; Han, Younghun; Hansen, Helen M.; Horsman, Janet; Kim, Claire; Lutz, Sharon; Rosenberger, Albert; Aben, Katja K.; Andrew, Angeline S.; Breslau, Naomi; Chang, Shen-Chih; Dieffenbach, Aida Karina; Dienemann, Hendrik; Frederiksen, Brittni; Han, Jiali; Hatsukami, Dorothy K.; Johnson, Eric O.; Pande, Mala; Wrensch, Margaret R.; McLaughlin, John R.; Skaug, Vidar; van der Heijden, Henricus F.; Wampfler, Jason; Wenzlaff, Angela; Woll, Penella; Zienolddiny, Shanbeh; Bickeböller, Heike; Brenner, Hermann; Duell, Eric J.; Haugen, Aage; Henrich, Joachim; Hokanson, John E.; Hunter, David J.; Kiemeney, Lambertus A.; Lazarus, Philip; Le Marchand, Loic; Liu, Geoffrey; Mayordomo, Jose; Risch, Angela; Schwartz, Ann G.; Teare, Dawn; Wu, Xifeng; Wiencke, John K.; Yang, Ping; Zhang, Zuo-Feng; Spitz, Margaret R.; Kraft, Peter; Amos, Christopher I.; Bierut, Laura J. (Peer reviewed; Journal article, 2015)
      Background: Recent meta-analyses show strong evidence of associations among genetic variants in CHRNA5 on chromosome 15q25, smoking quantity, and lung cancer. This meta-analysis tests whether the CHRNA5 variant rs16969968 ...

    • Copy number variation, increased gene expression, and molecular mechanisms of neurofascin in lung cancer 

      Samulin-Erdem, Johanna Maria; Arnoldussen, Yke Jildouw; Skaug, Vidar; Haugen, Aage; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2017)
      Metastasis and cell adhesion are key aspects of cancer progression. Neurofascin (NFASC) is a member of the immunoglobulin superfamily of adhesion molecules and, while studies on NFASC are inadequate, other members have ...

    • Criteria for grouping of manufactured nanomaterials to facilitate hazard and risk assessment, a systematic review of expert opinions. 

      Landvik, Nina Elisabeth; Skaug, Vidar; Mohr, Benedicte; Verbeek, Jos; Zienolddiny, Shanbeh (Journal article, 2018)
      With the emergence of nanotechnology the number of manufactured nanomaterials (MNM) in production and use is constantly increasing. Exposure of workers to MNM is of concern, because still much is unknown about health ...

    • Detection of multi-walled carbon nanotubes and carbon nanodiscs on workplace surfaces at a small-scale producer 

      Hedmer, Maria; Ludvigsson, Linus; Isaxon, Christina; Nilsson, Patrik T.; Skaug, Vidar; Bohgard, Mats; Pagels, Joakim H.; Messing, Maria E.; Tinnerberg, Håkan (Peer reviewed; Journal article, 2015)
      Background: The industrial use of novel-manufactured nanomaterials such as carbon nanotubes and carbon nanodiscs is increasing globally. Occupational exposure can occur during production, downstream use, and disposal. The ...

    • Differences in inflammation and acute phase response but similar genotoxicity in mice following pulmonary exposure to graphene oxide and reduced graphene oxide 

      Bengtson, Stefan; Knudsen, Kristina B.; Kyjovska, Zdenka O.; Berthing, Trine; Skaug, Vidar; Levin, Marcus; Koponen, Ismo K.; Shivayogimath, Abhay; Booth, Timothy J.; Alonso, Beatriz; Pesquera, Amaia; Zurutuza, Amaia; Thomsen, Birthe L; Troelsen, Jesper T; Jacobsen, Nicklas R; Vogel, Ulla (Peer reviewed; Journal article, 2017)
      We investigated toxicity of 2–3 layered >1 μm sized graphene oxide (GO) and reduced graphene oxide (rGO) in mice following single intratracheal exposure with respect to pulmonary inflammation, acute phase response (biomarker ...

    • Effects of carbon nanotubes on intercellular communication and involvement of IL-1 genes 

      Arnoldussen, Yke Jildouw; Anmarkrud, Kristine Haugen; Skaug, Vidar; Apte, Ron N.; Haugen, Aage; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2016)
      An increasing amount of products containing engineered nanoparticles is emerging. Among these particles are carbon nanotubes (CNTs) which are of interest for a wide range of industrial and biomedical applications. There ...

    • Effects on human bronchial epithelial cells following low-dose chronic exposure to nanomaterials: A 6-month transformation study 

      Phuyal, Santosh; Kasem, Mayes; Rubio, Laura; Karlsson, Hanna; Marcos, Ricard; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2017)
      The most plausible exposure route to manufactured nanomaterials (MNM) remains pulmonary inhalation. Yet, few studies have attempted to assess carcinogenic properties in vitro following long-term exposure of human pulmonary ...

    • Electron microscopy of particles deposited in the lungs of nickel refinery workers 

      Küpper, Miriam; Weinbruch, Stephan; Skaug, Vidar; Skogstad, Asbjørn; Thornér, Elin Einarsdóttir; Benker, Nathalie; Ebert, Martin; Chashchin, Valery; Odland, Jon Øyvind; Thomassen, Yngvar (Peer reviewed; Journal article, 2015)
      The size, morphology, and chemical composition of particles deposited in the lungs of two nickel refinery workers were studied by scanning and transmission electron microscopy. The particles were extracted from the lung ...

    • Elevated platelet count appears to be causally associated with increased risk of lung cancer. A Mendelian randomization analysis 

      Zhu, Ying; Wei, Yongyue; Zhang, Ruyang; Dong, Xuesi; Shen, Sipeng; Zhao, Yang; Bai, Jianling; Albanes, Demetrius; Caporaso, Neil E.; Landi, Maria Teresa; Zhu, Bin; Chanock, Stephen J.; Gu, Fangyi; Lam, Stephen; Ming-Sound, Tsao; Shepherd, Frances A.; Tardon, Adonina; Fernández-Somoano, Ana; Fernandez-Tardon, Guillermo; Chen, Chu; Barnett, Matthew J.; Doherty, Jennifer; Bojesen, Stig E.; Johansson, Mattias; Brennan, Paul; McKay, James D.; Carreras-Torres, Robert; Muley, Thomas; Risch, Angela; Wichmann, Heinz-Erich; Bickeboller, Heike; Rosenberger, Albert; Rennert, Gad; Saliba, Walid; Arnold, Susanne; Field, John K.; Davies, Michael P.A.; Marcus, Michael W.; Wu, Xifeng; Ye, Yuanqing; Le Marchand, Loic; Wilkens, Lynne R.; Melander, Olle; Manjer, Jonas; Brunnström, Hans; Hung, Rayjean J.; Liu, Geoffrey; Brhane, Yonathan; Kachuri, Linda; Andrew, Angeline S.; Duell, Eric J.; Kiemeney, Lambertus A.; van der Heijden, Erik H. F. M.; Haugen, Aage; Zienolddiny, Shanbeh; Skaug, Vidar; Grankvist, Kjell; Johansson, Mikael; Woll, Penella; Cox, Angela; Taylor, Fiona; Teare, Dawn; Lazarus, Philip; Schabath, Matthew B.; Aldrich, Melinda C.; Houlston, Richard S.; McLaughlin, John; Stevens, Victoria L.; Shen, Hongbing; Hu, Zhibin; Dai, Juncheng; Amos, Christopher I.; Han, Younghun; Zhu, Dakai; Goodman, Gary E.; Chen, Feng; Christiani, David C. (Peer reviewed; Journal article, 2019)
      Background: Platelets are a critical element in coagulation and inflammation, and activated platelets are linked to cancer risk through diverse mechanisms. However, a causal relationship between platelets and risk of lung ...

    • Estrogen receptor expression and gene promoter methylation in non-small cell lung cancer - a short report 

      Tekpli, Xavier; Skaug, Vidar; Bæra, Rita; Phillips, David H.; Haugen, Aage; Mollerup, Steen Kristen (Peer reviewed; Journal article, 2016)
      Purpose: In the past, anomalous estrogen receptor (ER) regulation has been associated with various lung pathologies, but so far its involvement in lung cancer initiation and/or progression has remained unclear. Here, we ...

    • Examination of nervous system effects and other health effects in tunnel workers exposed to acrylamide and N-methyloacrylamide in Romeriksporten, Norway 

      Kjuus, Helge; Goffeng, Lars Ole; Heier, Mona Skard; Hansteen, Inger-Lise; Øvrebø, Steinar; Skaug, Vidar; Ryberg, David; Sjöholm, Hans; Törnqvist, Margareta; Paulsson, Birgit; Langeland, B. T.; Brudal, Stein (STAMI-rapport; årgang 3, Nr. 5, Research report, 2002)

    • Exposure and emission measurements during production, purification, and functionalization of arc-discharge-produced multi-walled carbon nanotubes 

      Hedmer, Maria; Isaxon, Christina; Nilsson, Patrick T.; Ludvigsson, Linus; Messing, Maria; Genberg, Johan; Skaug, Vidar; Bohgard, Mats; Tinnerberg, Håkan; Pagels, Joakim (Peer reviewed; Journal article, 2014)
      Background: The production and use of carbon nanotubes (CNTs) is rapidly growing. With increased production, there is potential that the number of occupational exposed workers will rapidly increase. Toxicological studies ...