Blar i Brage på forfatter "Dirven, Hubert"
-
Exposure to human relevant mixtures of halogenated persistent organic pollutants (POPs) alters neurodevelopmental processes in human neural stem cells undergoing differentiation
Davidsen, Nichlas; Lauvås, Anna Jacobsen; Myhre, Oddvar; Ropstad, Erik; Carpi, Donatella; Mendoza-de Gyves, Emilio; Berntsen, Hanne Friis; Dirven, Hubert; Paulsen, Ragnhild Elisabeth; Bal-Price, Anna; Pistollato, Francesca (Peer reviewed; Journal article, 2021)Halogenated persistent organic pollutants (POPs) like perfluorinated alkylated substances (PFASs), brominated flame retardants (BFRs), organochlorine pesticides and polychlorinated biphenyls (PCBs) are known to cause cancer, ... -
Exposure to persistent organic pollutants alters the serum metabolome in non-obese diabetic mice
Sinioja, Tim; Bodin, Johanna Eva; Duberg, Daniel; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2022)Introduction Autoimmune disorders such as type 1 diabetes (T1D) are believed to be caused by the interplay between several genetic and environmental factors. Elucidation of the role of environmental factors in metabolic ... -
Prenatal exposure to perfluoroalkyl substances modulates neonatal serum phospholipids, increasing risk of type 1 diabetes
McGlinchey, Aidan; Sinioja, Tim; Lamichhane, Santosh; Sen, Partho; Bodin, Johanna Eva; Siljander, Heli; Dickens, Alex M.; Geng, Dawei; Carlsson, Cecilia; Duberg, Daniel; Ilonen, Jorma; Virtanen, Suvi M.; Dirven, Hubert; Berntsen, Hanne Friis; Zimmer, Karin Elisabeth; Nygaard, Unni Cecilie; Orešič, Matej; Knip, Mikael; Hyötyläinen, Tuulia (Peer reviewed; Journal article, 2020)In the last decade, increasing incidence of type 1 diabetes (T1D) stabilized in Finland, a phenomenon that coincides with tighter regulation of perfluoroalkyl substances (PFAS). Here, we quantified PFAS to examine their ...