• A human relevant mixture of persistent organic pollutants (POPs) and perfluorooctane sulfonic acid (PFOS) enhance nerve growth factor (NGF)-induced neurite outgrowth in PC12 cells 

      Yadav, Ajay; Amber, Mazia; Zosen, Denis; Labba, Nils Anders; Huiberts, Eva Henriette Willemijn; Samulin-Erdem, Johanna Maria; Haugen, Fred; Berntsen, Hanne Friis; Zienolddiny, Shanbeh; Paulsen, Ragnhild Elisabeth; Ropstad, Erik; Connolly, Lisa; Verhaegen, Steven (Peer reviewed; Journal article, 2020)
      Disruption of neurite outgrowth is a marker for neurotoxicity. Persistent organic pollutants (POPs) are potential developmental neurotoxicants. We investigated their effect on neurite outgrowth in PC12 rat pheochromocytoma ...
    • An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials 

      Bannuscher, Anne; Schmid, Otmar; Drasler, Barbara; Rohrbasser, Alain; Braakhuis, Hedwig M.; Meldrum, Kirsty; Zwart, Edwin P.; Gremmer, Eric R.; Birk, Barbara; Rissel, Manuel; Landsiedel, Robert; Moschini, Elisa; Evans, Stephen J.; Kumar, Pramod; Orak, Sezer; Doryab, Ali; Samulin-Erdem, Johanna Maria; Serchi, Tommaso; Vandebriel, Rob J.; Cassee, Flemming R.; Doak, Shareen H.; Petri-Fink, Alke; Zienolddiny, Shanbeh; Clift, Martin J.D.; Rothen-Rutishauser, Barbara (Peer reviewed; Journal article, 2022)
      Air-liquid interface (ALI) lung cell models cultured on permeable transwell inserts are increasingly used for respiratory hazard assessment requiring controlled aerosolization and deposition of any material on ALI cells. ...
    • Loss of MKK3 and MK2 copy numbers in non-small cell lung cancer 

      Samulin-Erdem, Johanna Maria; Skaug, Vidar; Haugen, Aage; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2016)
    • Mechanisms of Toxicity of Industrially Relevant Silicomanganese Dust on Human 1321N1 Astrocytoma Cells: An In Vitro Study 

      Arnoldussen, Yke Jildouw; Ervik, Torunn Kringlen; Samulin-Erdem, Johanna Maria; Kero, Ida; Eriksen, Mina Baarnes; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2019)
      Tremendous efforts are applied in the ferroalloy industry to control and reduce exposure to dust generated during the production process, as inhalable Mn-containing particulate matter has been linked to neurodegenerative ...
    • Mechanisms of Toxicity of Industrially Relevant Silicomanganese Dust on Human 1321N1 Astrocytoma Cells: An In Vitro Study 

      Arnoldussen, Yke Jildouw; Ervik, Torunn Kringlen; Samulin-Erdem, Johanna Maria; Kero, Ida; Eriksen, Mina Baarnes; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2019)
      Tremendous efforts are applied in the ferroalloy industry to control and reduce exposure to dust generated during the production process, as inhalable Mn-containing particulate matter has been linked to neurodegenerative ...
    • Multiwalled Carbon Nanotubes Induce Fibrosis and Telomere Length Alterations 

      Alswady-Hoff, Mayes; Samulin-Erdem, Johanna Maria; Aleksandersen, Mona; Anmarkrud, Kristine Haugen; Skare, Øivind; Lin, Fang-Chin; Simensen, Vincent; Arnoldussen, Yke Jildouw; Skaug, Vidar; Ropstad, Erik; Zienolddiny-Narui, Shanbeh (Peer reviewed; Journal article, 2022)
      Telomere shortening can result in cellular senescence and in increased level of genome instability, which are key events in numerous of cancer types. Despite this, few studies have focused on the effect of nanomaterial ...