• Advanced Respiratory Models for Hazard Assessment of Nanomaterials. Performance of Mono-, Co- and Tricultures 

      Camassa, Laura Maria Azzurra; Elje, Elisabeth; Mariussen, Espen; Longhin, Eleonora Marta; Dusinska, Maria; Zienolddiny-Narui, Shanbeh; Rundén-Pran, Elise (Peer reviewed; Journal article, 2022)
      Advanced in vitro models are needed to support next-generation risk assessment (NGRA), moving from hazard assessment based mainly on animal studies to the application of new alternative methods (NAMs). Advanced models must ...
    • High aspect ratio nanomaterial-induced macrophage polarization is mediated by changes in miRNA levels 

      Erdem, Johanna Samulin; Závodná, Táňa; Ervik, Torunn Kringlen; Skare, Øivind; Hron, Tomáš; Anmarkrud, Kristine H.; Kuśnierczyk, Anna; Catalán, Julia; Ellingsen, Dag; Topinka, Jan; Zienolddiny-Narui, Shanbeh (Peer reviewed; Journal article, 2023)
      Introduction: Inhalation of nanomaterials may induce inflammation in the lung which if left unresolved can manifest in pulmonary fibrosis. In these processes, alveolar macrophages have an essential role and timely modulation ...
    • Multiwalled Carbon Nanotubes Induce Fibrosis and Telomere Length Alterations 

      Alswady-Hoff, Mayes; Samulin-Erdem, Johanna Maria; Aleksandersen, Mona; Anmarkrud, Kristine Haugen; Skare, Øivind; Lin, Fang-Chin; Simensen, Vincent; Arnoldussen, Yke Jildouw; Skaug, Vidar; Ropstad, Erik; Zienolddiny-Narui, Shanbeh (Peer reviewed; Journal article, 2022)
      Telomere shortening can result in cellular senescence and in increased level of genome instability, which are key events in numerous of cancer types. Despite this, few studies have focused on the effect of nanomaterial ...