Browsing Brage by Journals "Nanotoxicology"

Now showing items 1-11 of 11

    • Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice 

      Hadrup, Niels; Rahmani, Feriel; Jacobsen, Nicklas R.; Saber, Anne T.; Jackson, Petra; Bengtson, Stefan; Williams, Andrew; Wallin, Håkan; Halappanavar, Sabina; Vogel, Ulla (Peer reviewed; Journal article, 2019)
      Inhalation of nanosized zinc oxide (ZnO) induces metal fume fever and systemic acute phase response in humans. Acute phase response activation is a cardiovascular risk factor; we investigated whether pulmonary exposure of ...

    • Bioinformatics and machine learning to support nanomaterial grouping 

      Bahl, Aileen; Halappanavar, Sabina; Wohlleben, Wendel; Nymark, Penny; Kohonen, Pekka; Wallin, Håkan; Vogel, Ulla; Haase, Andrea (Peer reviewed; Journal article, 2024)
      Nanomaterials (NMs) offer plenty of novel functionalities. Moreover, their physicochemical properties can be fine-tuned to meet the needs of specific applications, leading to virtually unlimited numbers of NM variants. ...

    • Characterization of the proteome and lipidome profiles of human lung cells after low dose and chronic exposure to multiwalled carbon nanotubes 

      Phuyal, Santosh; Kasem, Mayes; Knittelfelder, Oskar; Sharma, Animesh; Fonseca, Davi de Miranda; Vebraite, Vaineta; Shaposhnikov, Sergey; Slupphaug, Geir; Skaug, Vidar; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2018)
      The effects of long-term chronic exposure of human lung cells to multi-walled carbon nanotubes (MWCNT) and their impact upon cellular proteins and lipids were investigated. Since the lung is the major target organ, an in ...

    • Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes 

      Arnoldussen, Yke Jildouw; Skaug, Vidar; Aleksandersen, Mona; Ropstad, Erik; Anmarkrud, Kristine Haugen; Thornér, Elin Einarsdóttir; Lin, Fang-Chin; Bjørklund, Cesilie Granum; Kasem, Mayes; Eilertsen, Einar; Apte, Ron N.; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2018)

    • Inflammation in the pleural cavity following injection of multi-walled carbon nanotubes is dependent on their characteristics and the presence of IL-1 genes 

      Arnoldussen, Yke Jildouw; Skaug, Vidar; Aleksandersen, Mona; Ropstad, Erik; Anmarkrud, Kristine Haugen; Thornér, Elin Einarsdóttir; Lin, Fang-Chin; Bjørklund, Cesilie Granum; Kasem, Mayes; Ezzatpanah, Somayeh; Eilertsen, Einar; Apte, RN.; Zienolddiny, Shanbeh (Peer reviewed; Journal article, 2018)

    • Inflammation related to inhalation of nano and micron sized iron oxides: a systematic review 

      Moen, Aurora Lie; Johnsen, Helge; Hristozov, Danail; Zabeo, Alex; Pizzol, Lisa; Ibarrola, Oihane; Hannon, Gary; Holmes, Sarah; Zegeye, Fikirte Debebe; Vogel, Ulla; Mello, Adriele Prina; Zienolddiny-Narui, Shan; Wallin, Håkan (Peer reviewed; Journal article, 2024)
      Inhalation exposure to iron oxide occurs in many workplaces and respirable aerosols occur during thermal processes (e.g. welding, casting) or during abrasion of iron and steel products (e.g. cutting, grinding, machining, ...

    • Insights into possibilities for grouping and read-across for nanomaterials in EU chemicals legislation 

      Mech, A.; Rasmussen, K.; Jantunen, P.; Aicher, L.; Alessandrelli, M.; Bernauer, U.; Bleeker, E. A. J.; Bouillard, J.; Di Prospero Fanghella, P.; Draisci, R.; Dusinska, Maria; Encheva, G.; Flament, G.; Haase, A.; Handzhiyski, Y.; Herzberg, F.; Huwyler, J.; Jacobsen, N.R.; Jeliazkov, V.; Jeliazkova, N.; Nymark, P.; Grafström, R.; Oomen, A. G.; Polci, M. L.; Riebeling, C.; Sandström, J.; Shivachev, B.; Stateva, S.; Tanasescu, S.; Tsekovska, R.; Wallin, Håkan; Wilks, M. F.; Zellmer, S.; Apostolova, M. D. (Peer reviewed; Journal article, 2018)
      This paper presents a comprehensive review of European Union (EU) legislation addressing the safety of chemical substances, and possibilities within each piece of legislation for applying grouping and read-across approaches ...

    • Multi-walled carbon nanotube physicochemical properties predict pulmonary inflammation and genotoxicity 

      Poulsen, Sarah S.; Jackson, Petra; Kling, Kirsten; Knudsen, Kristina B.; Skaug, Vidar; Kyjovska, Zdenka O.; Thomsen, Birthe L.; Clausen, Per A.; Atluri, Rambabu; Berthing, Trine; Bengtson, Stefan; Wolff, Henrik; Jensen, Keld A.; Wallin, Håkan; Vogel, Ulla (Peer reviewed; Journal article, 2016)
      Lung deposition of multi-walled carbon nanotubes (MWCNT) induces pulmonary toxicity. Commercial MWCNT vary greatly in physicochemical properties and consequently in biological effects. To identify determinants of MWCNT-induced ...

    • Particulate matter constituents trigger the formation of extracellular amyloid β and Tau -containing plaques and neurite shortening in vitro 

      Sebastijanović, Aleksandar; Camassa, Laura Maria Azzurra; Malmborg, Vilhelm; Kralj, Slavko; Pagels, Joakim; Vogel, Ulla; Zienolddiny-Narui, Shan; Urbančič, Iztok; Koklič, Tilen; Štrancar, Janez (Peer reviewed; Journal article, 2024)
      Air pollution is an environmental factor associated with an increased risk of neurodegenerative diseases, such as Alzheimer’s and Parkinson’s, characterized by decreased cognitive abilities and memory. The limited models ...

    • Systematic review of mechanistic evidence for TiO2 nanoparticle-induced lung carcinogenicity 

      Wolf-Grosse, Susann; Sriram, Krishnan; Camassa, Laura Maria Azzurra; Pathakb, Dhruba; Bing, Helene L.; Mohr, Benedicte; Zienolddiny-Narui, Shan; Samulin-Erdem, Johanna Maria (Peer reviewed; Journal article, 2024)
      Nano-sized titanium dioxide particles (TiO2 NPs) are a high-production volume nanomaterial widely used in the paints, cosmetics, food and photovoltaics industry. However, the potential carcinogenic effects of TiO2 NPs in ...

    • Unchanged pulmonary toxicity of ZnO nanoparticles formulated in a liquid matrix for glass coating 

      Saber, Anne Thoustrup; Hadrup, Niels; Williams, Andrew; Mortensen, Alicja; Szarek, Józef; Kyjovska, Zdenka; Kurz, Alexander; Jacobsen, Nicklas Raun; Wallin, Håkan; Halappanavar, Sabina; Vogel, Ulla (Peer reviewed; Journal article, 2022)
      The inclusion of nanoparticles can increase the quality of certain products. One application is the inclusion of Zinc oxide (ZnO) nanoparticles in a glass coating matrix to produce a UV-absorbing coating for glass sheets. ...