Browsing Brage by Author "Øvrevik, Johan"
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A human relevant mixture of persistent organic pollutants induces reactive oxygen species formation in isolated human leucocytes: Involvement of the β2-adrenergic receptor
Berntsen, Hanne Friis; Bodin, Johanna Eva; Øvrevik, Johan; Berntsen, Christopher Friis; Østby, Gunn Charlotte; Brinchmann, Bendik Christian; Ropstad, Erik; Myhre, Oddvar (Peer reviewed; Journal article, 2021)Exposure to chlorinated (Cl), brominated (Br) and perfluoroalkyl acid (PFAA) persistent organic pollutants (POPs) is associated with immunotoxicity and other adverse effects in humans and animals. Previous studies on POPs ... -
A human relevant mixture of persistent organic pollutants induces reactive oxygen species formation in isolated human leucocytes: Involvement of the β2-adrenergic receptor
Berntsen, Hanne Friis; Bodin, Johanna Eva; Øvrevik, Johan; Berntsen, Christopher Friis; Østby, Gunn Charlotte; Brinchmann, Bendik Christian; Ropstad, Erik; Myhre, Oddvar (Peer reviewed; Journal article, 2021)Exposure to chlorinated (Cl), brominated (Br) and perfluoroalkyl acid (PFAA) persistent organic pollutants (POPs) is associated with immunotoxicity and other adverse effects in humans and animals. Previous studies on POPs ... -
A human relevant mixture of persistent organic pollutants induces reactive oxygen species formation in isolated human leucocytes: Involvement of the β2-adrenergic receptor
Berntsen, Hanne Friis; Bodin, Johanna Eva; Øvrevik, Johan; Berntsen, Christopher Friis; Østby, Gunn Charlotte; Brinchmann, Bendik Christian; Ropstad, Erik; Myhre, Oddvar (Peer reviewed; Journal article, 2021)Exposure to chlorinated (Cl), brominated (Br) and perfluoroalkyl acid (PFAA) persistent organic pollutants (POPs) is associated with immunotoxicity and other adverse effects in humans and animals. Previous studies on POPs ... -
Biological effects of combustion-derived particles from different biomass sources on human bronchial epithelial cells
Marchetti, Sara; Mollerup, Steen Kristen; Gutzkow, Kristine Bjerve; Rizzi, Cristiana; Skuland, Tonje Schwach; Refsnes, Magne Arnold; Colombo, Anita; Øvrevik, Johan; Mantecca, Paride; Holme, Jørn Andreas (Peer reviewed; Journal article, 2021)Combustion-derived particles (CDPs), in particular from traffic, are regarded as a central contributor for adverse health effects linked to air pollution. Recently, also biomass burning has been recognized as an important ... -
Characterization and pro‐inflammatory potential of indoor mold particles
Holme, Jørn Andreas; Øya, Elisabeth Tveiten; Afanou, Komlavi Anani; Øvrevik, Johan; Wijnand, Eduard (Peer reviewed; Journal article, 2020)A number of epidemiological studies find an association between indoor air dampness and respiratory health effects. This is often suggested to be linked to enhanced mold growth. However, the role of mold are obviously ... -
Effects of organic chemicals from diesel exhaust particles on adipocytes differentiated from human mesenchymal stem cells
Brinchmann, Bendik Christian; Holme, Jørn Andreas; Frerker, Nadine; Rambøl, Mia H.; Karlsen, Tommy Aleksander; Brinchmann, Jan E.; Kubátová, Alena; Kukowski, Klara; Skuland, Tonje Schwach; Øvrevik, Johan (Peer reviewed; Journal article, 2022)Exposure to fine particulate matter (PM2.5) from incomplete fossil fuel combustion (coal, oil, gas and diesel) has been linked to increased morbidity and mortality due to metabolic diseases. PM2.5 exaggerate adipose ... -
Hyphae fragments from A. fumigatus sensitize lung cells to silica particles (Min-U-Sil): Increased release of IL-1?
Øya, Elisabeth; Zegeye, Fikirte Debebe; Bølling, Anette Kocbach; Øvstebø, Reidun; Afanou, Komlavi Anani; Øvrevik, Johan; Refsnes, Magne Arnold; Holme, Jørn Andreas (Peer reviewed; Journal article, 2019)Exposure to particulate matter (PM), such as mineral particles and biological particles/components may be linked to aggravation of respiratory diseases, including asthma. Here we report that exposure to Aspergillus fumigatus ... -
Physico-chemical properties and biological effects of diesel and biomass particles
Longhin, Eleonora; Gualtieri, Maurizio; Capasso, Lauro; Bengalli, Rossella; Mollerup, Steen Kristen; Holme, Jørn Andreas; Øvrevik, Johan; Casadei, Simone; Di Benedetto, Christiano; Parenti, Paolo; Camatini, Marina (Peer reviewed; Journal article, 2016)Diesel combustion and solid biomass burning are the major sources of ultrafine particles (UFP) in urbanized areas. Cardiovascular and pulmonary diseases, including lung cancer, are possible outcomes of combustion particles ... -
Pro-inflammatory effects of crystalline- and nano-sized non-crystalline silica particles in a 3D alveolar model
Skuland, Tonje Schwach; Låg, Marit; Gutleb, Arno; Brinchmann, Bendik Christian; Serchi, Tommaso; Øvrevik, Johan; Holme, Jørn Andreas; Refsnes, Magne Arnold (Peer reviewed; Journal article, 2020)Background Silica nanoparticles (SiNPs) are among the most widely manufactured and used nanoparticles. Concerns about potential health effects of SiNPs have therefore risen. Using a 3D tri-culture model of the alveolar ... -
Pro-Inflammatory Responses in Human Bronchial Epithelial Cells Induced by Spores and Hyphal Fragments of Common Damp Indoor Molds
Øya, Elisabeth; Becher, Rune; Ekeren, Leni Johanne; Afanou, Komlavi Anani; Øvrevik, Johan; Holme, Jørn Andreas (Peer reviewed; Journal article, 2019)