Blar i Brage på forfatter "Jacobsen, Daniel Pitz"
-
Does ability to defend moderate the association between exposure to bullying and symptoms of anxiety?
Nielsen, Morten Birkeland; Gjerstad, Johannes; Jacobsen, Daniel Pitz; Einarsen, Ståle Valvatne (Peer reviewed; Journal article, 2017) -
Epiregulin is released from intervertebral disks and induces spontaneous activity in pain pathways
Kongstorp, Mette; Schjølberg, Tiril; Jacobsen, Daniel Pitz; Haugen, Fred; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Introduction: Lumbar radicular pain after disk herniation is associated with local release of many inflammatory molecules from nucleus pulposus (NP) cells leaking out of the intervertebral disk. Here, we have used a rat ... -
Exposure to workplace bullying, distress, and insomnia. The moderating role of the miR-146a genotype
Rajalingam, Dhaksshaginy; Jacobsen, Daniel Pitz; Nielsen, Morten Birkeland; Einarsen, Ståle; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Several lines of evidence show that systematic exposure to negative social acts at the workplace i.e., workplace bullying, results in symptoms of depression and anxiety among those targeted. However, little is known about ... -
Exposure to workplace bullying, microRNAs and pain. Evidence of a moderating effect of miR-30c rs928508 and miR-223 rs3848900
Jacobsen, Daniel Pitz; Eriksen, Mina Baarnes; Rajalingam, Dhaksshaginy; Nymoen, Ingeborg; Nielsen, Morten Birkeland; Einarsen, Ståle; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Prolonged exposure to bullying behaviors may give rise to symptoms such as anxiety, depression and chronic pain. Earlier data suggest that these symptoms often are associated with stress-induced low-grade systemic inflammation. ... -
Hyperexcitability in spinal WDR neurons following experimental disc herniation is associated with upregulation of fractalkine and its receptor in nucleus pulposus and the dorsal root ganglion
Jacobsen, Daniel Pitz; Moen, Aurora Lie; Haugen, Fred; Gjerstad, Johannes (Peer reviewed; Journal article, 2016)Introduction: Lumbar radicular pain following intervertebral disc herniation may be associated with a local inflammatory response induced by nucleus pulposus (NP) cells. Methods. In anaesthetized Lewis rats, extracellular ... -
Negative social acts and pain. Evidence of a workplace bullying and 5-HTT genotype interaction
Jacobsen, Daniel Pitz; Nielsen, Morten Birkeland; Einarsen, Ståle; Gjerstad, Johannes (Peer reviewed; Journal article, 2018)Objectives: Long-term exposure to systematic negative acts at work, usually labeled workplace bullying, is a prevalent problem at many workplaces. The adverse effects of such exposure may range from psychological symptoms, ... -
Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)
Rajalingam, Dhaksshaginy; Nymoen, Ingeborg; Jacobsen, Daniel Pitz; Eriksen, Mina Baarnes; Dissen, Erik; Nielsen, Morten Birkeland; Einarsen, Ståle; Gjerstad, Johannes (Peer reviewed; Journal article, 2020)Background Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ... -
Repeated social defeat promotes persistent inflammatory changes in splenic myeloid cells; decreased expression of β-arrestin-2 (ARRB2) and increased expression of interleukin-6 (IL-6)
Rajalingam, Dhaksshaginy; Nymoen, Ingeborg; Jacobsen, Daniel Pitz; Eriksen, Mina Baarnes; Dissen, Erik; Nielsen, Morten Birkeland; Einarsen, Ståle; Gjerstad, Johannes (Peer reviewed; Journal article, 2020)Background Previous studies suggest that persistent exposure to social stress in mammals may be associated with multiple physiological effects. Here, we examine the effects of social stress in rats, i.e. repeated social ... -
The 5-HTTLPR rs25531 LALA-genotype increases the risk of insomnia symptoms among shift workers
Pallesen, Ståle; Jacobsen, Daniel Pitz; Nielsen, Morten Birkeland; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Background Previous studies indicate that shift work tolerance may be associated with individual factors including genetic variability in the gene encoding the serotonin transporter 5-HTT (SLC6A4). The present study aimed ... -
The 5-HTTLPR rs25531 LALA-genotype increases the risk of insomnia symptoms among shift workers
Pallesen, Ståle; Jacobsen, Daniel Pitz; Nielsen, Morten Birkeland; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Background Previous studies indicate that shift work tolerance may be associated with individual factors including genetic variability in the gene encoding the serotonin transporter 5-HTT (SLC6A4). The present study aimed ... -
Up-regulation of circulating microRNA-17 is associated with lumbar radicular pain following disc herniation
Hasvik, Eivind Olay; Schjølberg, Tiril; Jacobsen, Daniel Pitz; Haugen, Anne Julsrud; Grøvle, Lars; Schistad, Ellina Iordanova; Gjerstad, Johannes (Peer reviewed; Journal article, 2019)Background: Previous studies suggest that regulatory microRNAs (miRs) may modulate neuro-inflammatory processes. The purpose of the present study was to examine the role of miR-17 following intervertebral disc herniation. ...