Browsing Brage by Author "Williams, Andrew"
Now showing items 1-6 of 6
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Acute phase response and inflammation following pulmonary exposure to low doses of zinc oxide nanoparticles in mice
Hadrup, Niels; Rahmani, Feriel; Jacobsen, Nicklas R.; Saber, Anne T.; Jackson, Petra; Bengtson, Stefan; Williams, Andrew; Wallin, Håkan; Halappanavar, Sabina; Vogel, Ulla (Peer reviewed; Journal article, 2019)Inhalation of nanosized zinc oxide (ZnO) induces metal fume fever and systemic acute phase response in humans. Acute phase response activation is a cardiovascular risk factor; we investigated whether pulmonary exposure of ... -
Multi-walled carbon nanotube-induced genotoxic, inflammatory and pro-fibrotic responses in mice: Investigating the mechanisms of pulmonary carcinogenesis
Rahman, Luna; Jacobsen, Nicklas Raun; Aziz, Syed Abdul; Wu, Dongmei; Williams, Andrew; Yauk, Carole L.; White, Paul; Wallin, Håkan; Vogel, Ulla; Halappanavar, Sabina (Peer reviewed; Journal article, 2017)The International Agency for Research on Cancer has classified one type of multi-walled carbon nanotubes (MWCNTs) as possibly carcinogenic to humans. However, the underlying mechanisms of MWCNT- induced carcinogenicity are ... -
Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses
Halappanavar, Sabina; Rahman, Luna; Nikota, Jake; Poulsen, Sarah S.; Ding, Yaobo; Jackson, Petra; Wallin, Håkan; Schmid, Otmar; Vogel, Ulla; Williams, Andrew (Peer reviewed; Journal article, 2019)Global transcriptomic responses in lungs of mice exposed for 24 h to individual multi-walled carbon nanotubes (MWCNTs, ten different types), nano titanium dioxide (nano TiO2, nine different types) and one type of carbon ... -
Single-Walled vs. Multi-Walled Carbon Nanotubes: Influence of Physico-Chemical Properties on Toxicogenomics Responses in Mouse Lungs
Solorio-Rodriguez, Silvia Aidee; Williams, Andrew; Poulsen, Sarah Søs; Knudsen, Kristina Bram; Jensen, Keld Alstrup; Clausen, Per Axel; Danielsen, Pernille Høgh; Wallin, Håkan; Vogel, Ulla; Halappanavar, Sabina (Peer reviewed; Journal article, 2023)Single-walled carbon nanotubes (SWCNTs) and multi-walled carbon nanotubes (MWCNTs) are nanomaterials with one or multiple layers of carbon sheets. While it is suggested that various properties influence their toxicity, the ... -
Stat-6 signaling pathway and not Interleukin-1 mediates multi-walled carbon nanotube-induced lung fibrosis in mice: insights from an adverse outcome pathway framework
Nikota, Jake; Banville, Allyson; Goodwin, Laura Rose; Wu, Dongmei; Williams, Andrew; Yauk, Carole Lynn; Wallin, Håkan; Vogel, Ulla; Halappanavar, Sabina (Peer reviewed; Journal article, 2017) -
Unchanged pulmonary toxicity of ZnO nanoparticles formulated in a liquid matrix for glass coating
Saber, Anne Thoustrup; Hadrup, Niels; Williams, Andrew; Mortensen, Alicja; Szarek, Józef; Kyjovska, Zdenka; Kurz, Alexander; Jacobsen, Nicklas Raun; Wallin, Håkan; Halappanavar, Sabina; Vogel, Ulla (Peer reviewed; Journal article, 2022)The inclusion of nanoparticles can increase the quality of certain products. One application is the inclusion of Zinc oxide (ZnO) nanoparticles in a glass coating matrix to produce a UV-absorbing coating for glass sheets. ...