| dc.contributor.author | Hansen, Kristine Eraker Aasland | |
| dc.contributor.author | Hudecova, Alexandra Misci | |
| dc.contributor.author | Haugen, Fred | |
| dc.contributor.author | Skjerve, Eystein | |
| dc.contributor.author | Ropstad, Erik | |
| dc.contributor.author | Zimmer, Karin Elisabeth | |
| dc.date.accessioned | 2022-10-20T12:28:34Z | |
| dc.date.available | 2022-10-20T12:28:34Z | |
| dc.date.created | 2022-10-10T12:51:12Z | |
| dc.date.issued | 2022 | |
| dc.identifier.citation | Laboratory Animal Research (LAR). 2022, 38 . | |
| dc.identifier.issn | 1738-6055 | |
| dc.identifier.uri | https://hdl.handle.net/11250/3027320 | |
| dc.description.abstract | BACKGROUND All mouse strains are different, before choosing a strain for a large study, a small scale study should be done. In this study, we compared young males of two mouse strains, C57BL/6J and the hybrid B6129SF1/J, and gained knowledge on their performance in three different behavioral tests; open field (OF) test, Barnes maze (BM) test and a restraint stress test. RESULTS We found that the young males of the C57BL/6J strain spent more time moving in the OF. In the BM, the hybrid covered less ground before reaching the goal box during the first three sessions, than the C57BL/6J. The hybrid left more fecal pellets than C57BL/6J both in OF and BM. During the stress test, the C57BL/6J had a lower corticosterone response than the hybrid. CONCLUSIONS Our findings indicate that the C57BL/6J has a presumably higher locomotor activity and/or explorative behavior than the hybrid, while the hybrid appeared more sensitive to stress. | |
| dc.description.abstract | Comparison of young male mice of two different strains (C57BL/6J and the hybrid B6129SF1/J) in selected behavior tests. A small scale study | |
| dc.language.iso | eng | |
| dc.title | Comparison of young male mice of two different strains (C57BL/6J and the hybrid B6129SF1/J) in selected behavior tests. A small scale study | |
| dc.title.alternative | Comparison of young male mice of two different strains (C57BL/6J and the hybrid B6129SF1/J) in selected behavior tests. A small scale study | |
| dc.type | Peer reviewed | |
| dc.type | Journal article | |
| dc.description.version | publishedVersion | |
| dc.source.pagenumber | 7 | |
| dc.source.volume | 38 | |
| dc.source.journal | Laboratory Animal Research (LAR) | |
| dc.identifier.doi | 10.1186/s42826-022-00140-5 | |
| dc.identifier.cristin | 2060049 | |
| cristin.ispublished | true | |
| cristin.fulltext | original | |
| cristin.qualitycode | 1 | |
