dc.contributor.author | Matre, Dagfinn | |
dc.contributor.author | Hu, Lu | |
dc.contributor.author | Viken, Leif Andre | |
dc.contributor.author | Hjelle, Ingri Berild | |
dc.contributor.author | Wigemyr, Monica | |
dc.contributor.author | Knardahl, Stein | |
dc.contributor.author | Sand, Trond | |
dc.contributor.author | Nilsen, Kristian Bernhard | |
dc.date.accessioned | 2024-09-09T07:34:26Z | |
dc.date.available | 2024-09-09T07:34:26Z | |
dc.date.created | 2015-10-28T14:19:51Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Sleep. 2015, 38 (10), 1607-1617. | |
dc.identifier.issn | 0161-8105 | |
dc.identifier.uri | https://hdl.handle.net/11250/3150854 | |
dc.description.abstract | Study Objectives: Sleep restriction (SR) has been hypothesized to sensitize the pain system. The current study determined whether experimental sleep restriction had an effect on experimentally induced pain and pain-elicited electroencephalographic (EEG) responses. Design: A paired crossover study. Intervention: Pain testing was performed after 2 nights of 50% SR and after 2 nights with habitual sleep (HS). Setting: Laboratory experiment at research center. Participants: Self-reported healthy volunteers (n = 21, age range: 18–31 y). Measurements and Results: Brief high-density electrical stimuli to the forearm skin produced pinprick-like pain. Subjective pain ratings increased after SR, but only in response to the highest stimulus intensity (P = 0.018). SR increased the magnitude of the pain-elicited EEG response analyzed in the time-frequency domain (P = 0.021). Habituation across blocks did not differ between HS and SR. Event-related desynchronization (ERD) was reduced after SR (P = 0.039). Pressure pain threshold of the trapezius muscle region also decreased after SR (P = 0.017). Conclusion: Sleep restriction (SR) increased the sensitivity to pressure pain and to electrically induced pain of moderate, but not low, intensity. The increased electrical pain could not be explained by a difference in habituation. Increased response magnitude is possibly related to reduced processing within the somatosensory cortex after partial SR. | |
dc.description.abstract | Experimental sleep restriction facilitates pain and electrically induced cortical responses | |
dc.language.iso | eng | |
dc.rights | Attribution 4.0 International | |
dc.rights.uri | https://creativecommons.org/licenses/by/4.0/ | |
dc.title | Experimental sleep restriction facilitates pain and electrically induced cortical responses | |
dc.title.alternative | Experimental sleep restriction facilitates pain and electrically induced cortical responses | |
dc.type | Peer reviewed | |
dc.type | Journal article | |
dc.description.version | publishedVersion | |
dc.source.pagenumber | 1607-1617 | |
dc.source.volume | 38 | |
dc.source.journal | Sleep | |
dc.source.issue | 10 | |
dc.identifier.doi | 10.5665/sleep.5058 | |
dc.identifier.cristin | 1284283 | |
cristin.ispublished | true | |
cristin.fulltext | original | |
cristin.qualitycode | 2 | |