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dc.contributor.authorMatre, Dagfinn
dc.contributor.authorHu, Lu
dc.contributor.authorViken, Leif Andre
dc.contributor.authorHjelle, Ingri Berild
dc.contributor.authorWigemyr, Monica
dc.contributor.authorKnardahl, Stein
dc.contributor.authorSand, Trond
dc.contributor.authorNilsen, Kristian Bernhard
dc.date.accessioned2024-09-09T07:34:26Z
dc.date.available2024-09-09T07:34:26Z
dc.date.created2015-10-28T14:19:51Z
dc.date.issued2015
dc.identifier.citationSleep. 2015, 38 (10), 1607-1617.
dc.identifier.issn0161-8105
dc.identifier.urihttps://hdl.handle.net/11250/3150854
dc.description.abstractStudy Objectives: Sleep restriction (SR) has been hypothesized to sensitize the pain system. The current study determined whether experimental sleep restriction had an effect on experimentally induced pain and pain-elicited electroencephalographic (EEG) responses. Design: A paired crossover study. Intervention: Pain testing was performed after 2 nights of 50% SR and after 2 nights with habitual sleep (HS). Setting: Laboratory experiment at research center. Participants: Self-reported healthy volunteers (n = 21, age range: 18–31 y). Measurements and Results: Brief high-density electrical stimuli to the forearm skin produced pinprick-like pain. Subjective pain ratings increased after SR, but only in response to the highest stimulus intensity (P = 0.018). SR increased the magnitude of the pain-elicited EEG response analyzed in the time-frequency domain (P = 0.021). Habituation across blocks did not differ between HS and SR. Event-related desynchronization (ERD) was reduced after SR (P = 0.039). Pressure pain threshold of the trapezius muscle region also decreased after SR (P = 0.017). Conclusion: Sleep restriction (SR) increased the sensitivity to pressure pain and to electrically induced pain of moderate, but not low, intensity. The increased electrical pain could not be explained by a difference in habituation. Increased response magnitude is possibly related to reduced processing within the somatosensory cortex after partial SR.
dc.description.abstractExperimental sleep restriction facilitates pain and electrically induced cortical responses
dc.language.isoeng
dc.rightsAttribution 4.0 International
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/
dc.titleExperimental sleep restriction facilitates pain and electrically induced cortical responses
dc.title.alternativeExperimental sleep restriction facilitates pain and electrically induced cortical responses
dc.typePeer reviewed
dc.typeJournal article
dc.description.versionpublishedVersion
dc.source.pagenumber1607-1617
dc.source.volume38
dc.source.journalSleep
dc.source.issue10
dc.identifier.doi10.5665/sleep.5058
dc.identifier.cristin1284283
cristin.ispublishedtrue
cristin.fulltextoriginal
cristin.qualitycode2


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International