Browsing Brage by Author "Schmid, Otmar"

Now showing items 1-4 of 4

    • An inter-laboratory effort to harmonize the cell-delivered in vitro dose of aerosolized materials 

      Bannuscher, Anne; Schmid, Otmar; Drasler, Barbara; Rohrbasser, Alain; Braakhuis, Hedwig M.; Meldrum, Kirsty; Zwart, Edwin P.; Gremmer, Eric R.; Birk, Barbara; Rissel, Manuel; Landsiedel, Robert; Moschini, Elisa; Evans, Stephen J.; Kumar, Pramod; Orak, Sezer; Doryab, Ali; Samulin-Erdem, Johanna Maria; Serchi, Tommaso; Vandebriel, Rob J.; Cassee, Flemming R.; Doak, Shareen H.; Petri-Fink, Alke; Zienolddiny, Shanbeh; Clift, Martin J.D.; Rothen-Rutishauser, Barbara (Peer reviewed; Journal article, 2022)
      Air-liquid interface (ALI) lung cell models cultured on permeable transwell inserts are increasingly used for respiratory hazard assessment requiring controlled aerosolization and deposition of any material on ALI cells. ...

    • Pulmonary toxicity of Fe2O3, ZnFe2O4, NiFe2O4 and NiZnFe4O8 nanomaterials. Inflammation and DNA strand breaks 

      Hadrup, Niels; Saber, Anne T.; Kyjovska, Zdenka O.; Jacobsen, Nicklas R.; Vippola, Minnamari; Sarlin, Essi; Ding, Yaobo; Schmid, Otmar; Wallin, Håkan; Jensen, Keld A. ; Vogel, Ulla (Peer reviewed; Journal article, 2019)
      Exposure to metal oxide nanomaterials potentially occurs at the workplace. We investigated the toxicity of two Fe-oxides: Fe2O3 nanoparticles and nanorods; and three MFe2O4 spinels: NiZnFe4O8, ZnFe2O4, and NiFe2O4 ...

    • Ranking of nanomaterial potency to induce pathway perturbations associated with lung responses 

      Halappanavar, Sabina; Rahman, Luna; Nikota, Jake; Poulsen, Sarah S.; Ding, Yaobo; Jackson, Petra; Wallin, Håkan; Schmid, Otmar; Vogel, Ulla; Williams, Andrew (Peer reviewed; Journal article, 2019)
      Global transcriptomic responses in lungs of mice exposed for 24 h to individual multi-walled carbon nanotubes (MWCNTs, ten different types), nano titanium dioxide (nano TiO2, nine different types) and one type of carbon ...

    • Transferability and reproducibility of exposed air-liquid interface co-culture lung models 

      Braakhuis, Hedwig M.; Gremmer, Eric R.; Bannuscher, Anne; Drasler, Barbara; Keshavan, Sandeep; Rothen-Rutishauser, Barbara; Birk, Barbara; Verlohner, Andreas; Landsiedel, Robert; Meldrum, Kirsty; Doak, Shareen H.; Clift, Martin J.D.; Samulin-Erdem, Johanna Maria; Foss, Oda Astrid Haarr; Zienolddiny, Shanbeh; Serchi, Tommaso; Moschini, Elisa; Weber, Pamina; Burla, Sabina; Kumar, Pramod; Schmid, Otmar; Zwart, Edwin; Vermeulen, Jolanda P.; Vandebriel, Rob J. (Peer reviewed; Journal article, 2023)
      The establishment of reliable and robust in vitro models for hazard assessment, a prerequisite for moving away from animal testing, requires the evaluation of model transferability and reproducibility. Lung models that can ...